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. 2018 Jun 13;37:116. doi: 10.1186/s13046-018-0780-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — TRIM52 up-regulation regulates p21, MMP2, PPM1A, p-Smad2/3 and Smad2/3 expression in HCC cells. After MHCC-97H (a, b) and MHCC-97L cells (c, d) transfection as Fig. 2 described, the expression of p21, MMP2, PPM1A, p-Smad2/3 and Smad2/3 was measured by Western blot analysis. **P < 0.01 compared with corresponding NC or Vector