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. 2018 Feb 17;40(2):120–131. doi: 10.1016/j.htct.2017.12.003

Figure 4.

Figure 4

Immune profile of healthy subjects (CTRL) and patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocythemia (ET). (A) Plasma levels of GM-CSF, IFN-α, IFN-γ, IL-1β, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17A, IP-10, MCP-1, MIP-1α, MIP-1β, RANTES, and TNF-α were used for categorical classification of CTRL, PMF, PV and ET groups as high or low producers of a given cytokine/chemokine. Black and white blocks represent high and low producers of each cytokine/chemokine, respectively. Each column represents a cytokine/chemokine, and each block represents each individual's cytokine/chemokine production pattern. The numbers below each column represent the frequency of high producers of the cytokine/chemokine tested.

(B) Radar chart representation of the immune profile of healthy subjects (CTRL) and patients with essential thrombocythemia (ET), primary myelofibrosis (PMF), and polycythemia vera (PV). Radar charts summarize the percentage of high producers of each cytokine/chemokine in the study groups. The plasma levels of GM-CSF, IFN-α, IFN-γ, IL-1β, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17A, IP-10, MCP-1, MIP-1α, MIP-1β, RANTES, and TNF-α were used for categorical classification of the CTRL, PMF, PV, and ET groups as high and low producers of a given cytokine/chemokine.