Skip to main content
. Author manuscript; available in PMC: 2018 Jun 14.
Published in final edited form as: J Am Chem Soc. 2018 May 15;140(20):6226–6230. doi: 10.1021/jacs.8b03459

Figure 1.

Figure 1

(A) van ’t Hoff plots from which thermodynamic constants are extracted for binding between complementary linear strands and either linear 12-mer DNA (blue) or SNAs (red). (B) Comparison of enthalpic gain and entropic cost derived from the van’t Hoff plots. (C) Isothermal titration calorimetry of 12-mer DNA duplex hybridization free in solution and (D) 12-mer DNA duplex hybridization on SNAs functionalized with ~46 strands per particle. Upper panel: differential heating power ΔP vs time. Lower panel: integrated heats of reaction Q vs molar ratio.