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Western blot analysis of signaling cascades in liver samples of 6-month-old fasted GHR-KO (n = 5) and control pigs (n = 4). (A) Insulin receptor-related signaling pathway and PPARG. (B) GHR- and mTOR-related signaling pathways. The box plots show medians, 25th and 75th percentiles (box), and extremes (whiskers). *p < 0.05; °p = 0.0635; evaluated using the Mann–Whitney U test.
