Table 2.
Control group | Experimental group | ||
---|---|---|---|
No. of animals examined | 5 | 5 | |
Adhesions | |||
Lung and chest wall (+) | 1 (1) | 2 (2) | |
Pulmonary interlobular (+) | 3 (3) | 2 (2) | |
Pleura | |||
Fibrosis (+/++) | 5 (2/3) | 5 (0/5) | |
Mesothelial cell hypertrophy (+) | 4 (4) | 5 (5) | |
Alveoli | |||
Epithelial cell cuboidal epithelialization (+/++) | 3 (3/0) | 5 (4/1) | |
Mononuclear cell infiltration (+) | 3 (3) | 1 (1) | |
Interstitium | |||
Mononuclear cell infiltration (+/++) | 4 (4/0) | 3 (2/1) |
Criteria for histopathological classification: Adhesions: +, present; Fibrosis in the pleura: +, localised; ++, diffuse; Mesothelial cell hypertrophy in the pleura: +, mild; Alveolar epithelial cell cuboidal epithelialization: +, localised; ++, diffuse; Alveolar mononuclear cell infiltration: +, localised; Interstitial mononuclear cell infiltration: +, localised; ++, diffuse.