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. 2018 Apr 27;15(7):689–695. doi: 10.7150/ijms.24050

Table 2.

Incidence of histopathological changes in the left lung and left chest wall

Control group Experimental group
No. of animals examined 5 5
Adhesions
Lung and chest wall (+) 1 (1) 2 (2)
Pulmonary interlobular (+) 3 (3) 2 (2)
Pleura
Fibrosis (+/++) 5 (2/3) 5 (0/5)
Mesothelial cell hypertrophy (+) 4 (4) 5 (5)
Alveoli
Epithelial cell cuboidal epithelialization (+/++) 3 (3/0) 5 (4/1)
Mononuclear cell infiltration (+) 3 (3) 1 (1)
Interstitium
Mononuclear cell infiltration (+/++) 4 (4/0) 3 (2/1)

Criteria for histopathological classification: Adhesions: +, present; Fibrosis in the pleura: +, localised; ++, diffuse; Mesothelial cell hypertrophy in the pleura: +, mild; Alveolar epithelial cell cuboidal epithelialization: +, localised; ++, diffuse; Alveolar mononuclear cell infiltration: +, localised; Interstitial mononuclear cell infiltration: +, localised; ++, diffuse.