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. 2017 Nov 21;47(6):1475–1486. doi: 10.1002/jmri.25901

Table 3.

Histogram Parameters of ADC, D, D*, and f for the Individual Malignant Tumor Types

Mean Median 5th % 25th % 75th % 90th % Kurtosis Skewness Entropy
HB n = 4 ADC 1181 ± 71 1104 ± 77 767 ± 110 972 ± 66 1301 ± 96 1632 ± 96 2.19 ± 4.0 × 10−2 3.1 × 10−2 ± 1.6 × 10−3 6.91 ± 2.2 × 10−1
D 962 ± 61 938 ± 51 386 ± 131 791 ± 60 1096 ± 65 1356 ± 71 2.21 ± 6.5 × 10−3 3.4 × 10−2 ± 3.4 × 10−4 7.01 ± 8.4 × 10−2
D* 18723 ± 1878 16144 ± 1933 5068 ± 589 11042 ± 1295 24000 ± 2616 33940 ± 3412 2.22 ± 3.0 × 10−2 7.3 × 10−3 ± 4.3 × 10−4 9.78 ± 1.8 × 10−1
f 16.6 ± 1.53 14.3 ± 1.43 4.00 ± 0.94 9.00 ± 1.17 20.8 ± 1.78 31.3 ± 2.48 2.15 ± 2.8 × 10−2 2.2 × 10−1 ± 8.4 × 10−3 3.60 ± 7.0 × 10−2
NB n = 11 ADC 1164 ± 190 1070 ± 201 625 ± 124 825 ± 139 1416 ± 271 1770 ± 352 2.22 ± 7.5 × 10−2 3.3 × 10−2 ± 5.7 × 10−3 7.09 ± 3.9 × 10−1
D 885 ± 88 817 ± 85 374 ± 102 616 ± 76 1098 ± 114 1413 ± 157 2.15 ± 5.7 × 10−2 3.0 × 10−2 ± 6.4 × 10−3 7.04 ± 2.3 × 10−1
D* 19348 ± 1213 16957 ± 1318 5120 ± 608 10651 ± 1457 24127 ± 1762 35328 ± 2118 2.22 ± 1.6 × 10−2 7.3 × 10−3 ± 1.9 × 10−4 9.30 ± 5.6 × 10−1
f 21.1 ± 1.85 17.1 ± 1.75 3.82 ± 0.47 9.72 ± 1.09 28.6 ± 3.04 43.1 ± 4.27 2.20 ± 1.9 × 10−2 2.1 × 10−1 ± 6.4 × 10−3 3.88 ± 1.2 × 10−1
W n = 8 ADC 1033 ± 191 939 ± 178 643 ± 103 795 ± 138 1180 ± 243 1511 ± 317 2.19 ± 5.4 × 10−2 3.5 × 10−2 ± 2.9 × 10−3 6.95 ± 3.2 × 10−1
D 935 ± 94 847 ± 85 586 ± 42 722 ± 63 1060 ± 120 1368 ± 167 2.19 ± 3.1 × 10−2 3.4 × 10−2 ± 1.7 × 10−3 6.86 ± 2.0 × 10−1
D* 14944 ± 791 13004 ± 787 4762 ± 729 9429 ± 655 18147 ± 1104 25530 ± 1683 2.21 ± 1.2 × 10−2 7.8 × 10−3 ± 3.8 × 10−5 9.84 ± 7.5 × 10−2
f 11.0 ± 0.80 9.00 ± 0.50 2.75 ± 0.41 6.50 ± 0.50 13.1 ± 0.92 20.3 ± 2.69 2.07 ± 3.6 × 10−2 1.9 × 10−1 ± 2.9 × 10−2 3.60 ± 7.0 × 10−2

HB: Hepatoblastoma; NB: Neuroblastoma; W: Wilms' tumor. Data presented correspond to mean values ± standard deviations. The units for mean, median, and percentiles of ADC, D, and D* are in × 10−6 mm2/s and f as a percentage (%).