Table 4.
Diagnostic Performance of D* and f Histogram Parameters in Discriminating Wilms' Tumor From Neuroblastoma
| Parameters | Mean | Median | 5th % | 25th % | 75th % | 90th % | Kurtosis | Skewness | Entropy | |
|---|---|---|---|---|---|---|---|---|---|---|
| D* | AUC | 0.909 | 0.909 | 0.506 | 0.675 | 0.909 | 0.935 | 0.571 | 0.909 | 0.532 |
| Confidence interval | 0.739, 1.00 | 0.739, 1.00 | 0.177, 0.836 | 0.408, 0.942 | 0.739, 1.00 | 0.807, 1.00 | 0.285, 0.858 | 0.739, 1.00 | 0.254, 0.811 | |
| Sensitivity % | 90.9 | 90.9 | 81.8 | 81.8 | 90.9 | 90.9 | 63.6 | 90.9 | 45.5 | |
| Specificity % | 100 | 100 | 57.1 | 71.4 | 100 | 100 | 85.7 | 100 | 100 | |
| P value | 0.004 | 0.004 | 0.964 | 0.221 | 0.004 | 0.002 | 0.618 | 0.004 | 0.821 | |
| Cutoff | 17826 | 15636 | 5471 | 9612 | 22044 | 32376 | 2.22 | 7.60 × 10−3 | 9.62 | |
| f | AUC | 1.00 | 1.00 | 0.784 | 0.938 | 1.00 | 0.966 | 0.886 | 0.523 | 0.977 |
| Confidence interval | 1.00, 1.00 | 1.00, 1.00 | 0.574, 0.994 | 0.835, 1.00 | 1.00, 1.00 | 0.889, 1.00 | 0.676, 1.00 | 0.245, 0.801 | 0.920, 1.00 | |
| Sensitivity % | 100 | 100 | 50.0 | 75.0 | 100 | 87.5 | 87.5 | 50.0 | 87.5 | |
| Specificity % | 100 | 100 | 90.9 | 90.9 | 100 | 100 | 100 | 72.7 | 100 | |
| P value | <0.001 | <0.001 | 0.039 | 0.001 | <0.001 | 0.001 | 0.005 | 0.869 | 0.029 | |
| Cutoff | 14.7 | 11.0 | 2.50 | 7.50 | 17.5 | 24.50 | 2.10 | 2.01 × 10−1 | 3.35 |
AUC is the area under the ROC curve. The units for mean, median, and percentiles of D* cutoff values are in ×10−6 mm2/s and f as a percentage (%).