Figure 5.

Effect of Aneustat on the relative levels of human CD8⁺ cells and FOXP3⁺ cells in first‐generation patient‐derived prostate cancer tissue xenografts. NSG mice bearing first‐generation prostate cancer tissue xenografts were treated for 3 weeks with Aneustat (1,652 mg/kg) or vehicle control. (a) The number of CD8⁺ T cells and (b) FOXP3⁺ Treg cells in the xenografts were determined using a 200× magnification. ***p < 0.001; NS: not significant. [Color figure can be viewed at http://wileyonlinelibrary.com]