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. 2018 Mar 26;124(11):2427–2437. doi: 10.1002/cncr.31318

Table 3.

Univariate Analysis by the Kaplan‐Meier Methoda

Characteristic PFS LRFS RRFS DMFS
Sex 0.15 0.059 0.56 0.42
Age (≤50 y vs >50 y) 0.37 0.70 0.38 0.12
Time to disease recurrence (≤2 y vs >2 y) 0.23 0.37 0.30 0.18
T classification (T1/2 vs T3/4) 0.38 0.59 0.50 0.49
N classification (N+ vs N‐) 0.14 0.12 0.56 0.42
Chemotherapyb 0.13 0.43 0.50 0.51
GTV dose (<60 GyE vs ≥60 GyE) 0.19 0.30 0.61 0.37
Fractionation (<3 GyE vs 3 GyE) 0.027 0.058 0.48 0.24
BED (<74.1 GyE vs ≥74.1 GyE)c 0.035 0.10 0.50 0.26

Abbreviations: BED, biological equivalent dose; DMFS, distant metastasis‐free survival, GTV, gross (macroscopic) tumor volume; GyE, Gray equivalent; LRFS, local recurrence‐free survival; PFS, progression‐free survival; RRFS, regional recurrence‐free survival.

a

Bold type indicates statistical significance.

b

Induction and/or concurrent chemotherapy.

c

The median BED was 74.1 GyE.