Figure 5.

Effects of miR‐34b‐5p inhibition on LPS‐induced lung injury. Mice were subjected to LPS after administration of the miR‐34b‐5p antagomir or NC for 48 hr. (a) Quantitation of the transfection efficiency of the miR‐34b‐5p antagomir in vivo. (b) Quantitation of the lung injury scores in the different treatment groups. (c) Representative images of lung lesions in the lung sections per HE staining. Scale bar = 50 μm, n = 4. (d) Representative images of neutrophils infiltration in lung sections by immunohistochemical staining. scale bar = 50µm, n = 4. (e) Quantitation of the number of neutrophils per HPF. (f) Quantitation of the number of macrophages per HPF. (g) Representative images of macrophage infiltration in lung sections per immunohistochemical staining. Scale bar = 50 μm, n = 4. *p < 0.05. Data are presented as the mean ± SD