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. 2018 Mar 30;177(4):416–425. doi: 10.1002/ajmg.b.32630

Table 3.

Schizophrenia, bipolar disorder, and major depression polygenic risk scores predicting psychotic‐like experience domains in adolescents

Specific PE β SE P r 2 (%) pTa
Schizophrenia
Paranoia and hallucinations −0.005 0.011 .664 0.002 0.200
Paranoia and hallucinations excl. zero scorers 0.031 0.012 7.90 × 10−3 0.094 0.001
Anhedonia 0.028 0.013 .030 0.079 0.100
Cognitive disorganization 0.029 0.014 .035 0.083 0.010
Parent‐rated negative symptoms 0.030 0.011 5.41 × 10−3 0.088 0.050
Bipolar disorder
Paranoia and hallucinations −0.034 0.011 2.47 × 10−3 0.115 0.010
Anhedonia −0.017 0.013 .178 0.030 0.100
Cognitive disorganization −0.013 0.014 .333 0.017 0.001
Parent‐rated negative symptoms −0.009 0.011 .388 0.008 0.500
Major depression
Paranoia and hallucinations 0.006 0.011 .589 0.004 0.100
Anhedonia 0.033 0.013 .010 0.109 0.500
Cognitive disorganization 0.018 0.014 .189 0.033 0.050
Parent‐rated negative symptoms 0.028 0.011 8.29 × 10−3 0.078 0.001

This table shows results for polygenic risk scores at the most predictive p‐value threshold for each trait.

Statistically significant results are highlighted in bold.

a

p‐value threshold used to select when calculating polygenic risk scores.