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. 2018 Mar 30;177(4):416–425. doi: 10.1002/ajmg.b.32630

Table 4.

Genetic covariance between each psychotic‐like experience domain and schizophrenia, bipolar disorder, and major depression

AVENGEME LDSC
Specific PE cov(G)a Low 95% CI High 95% CI cov(G)a SE p
Schizophrenia
Paranoia and hallucinations −0.002 −0.013 0.008 −0.003 0.014 .844
Paranoia and hallucinations excl. zero scorers 0.019 0.011 0.029 NA NA NA
Anhedonia 0.024 0.013 0.038 0.021 0.016 .184
Cognitive disorganization 0.025 0.013 0.040 0.054 0.018 3.52 × 10−3
Parent‐rated negative symptoms 0.025 0.015 0.036 0.047 0.014 5.57 × 10−4
Bipolar disorder
Paranoia and hallucinations −0.032 −0.048 −0.018 −0.045 0.022 .039
Anhedonia −0.022 −0.041 −0.002 0.008 0.028 .767
Cognitive disorganization 0.008 −0.013 0.029 0.021 0.028 .451
Parent‐rated negative symptoms −0.010 −0.026 0.006 0.009 0.021 .669
Major depressive disorder
Paranoia and hallucinations 0.004 −0.018 0.026 0.013 0.020 .523
Anhedonia 0.065 0.037 0.094 0.061 0.023 7.50 × 10−3
Cognitive disorganization 0.033 0.005 0.062 0.015 0.028 .594
Parent‐rated negative symptoms 0.023 0.010 0.042 0.031 0.020 .119

Statistically significant results are highlighted in bold.

a

Genetic covariance.