Table 4.
AVENGEME | LDSC | |||||
---|---|---|---|---|---|---|
Specific PE | cov(G)a | Low 95% CI | High 95% CI | cov(G)a | SE | p |
Schizophrenia | ||||||
Paranoia and hallucinations | −0.002 | −0.013 | 0.008 | −0.003 | 0.014 | .844 |
Paranoia and hallucinations excl. zero scorers | 0.019 | 0.011 | 0.029 | NA | NA | NA |
Anhedonia | 0.024 | 0.013 | 0.038 | 0.021 | 0.016 | .184 |
Cognitive disorganization | 0.025 | 0.013 | 0.040 | 0.054 | 0.018 | 3.52 × 10−3 |
Parent‐rated negative symptoms | 0.025 | 0.015 | 0.036 | 0.047 | 0.014 | 5.57 × 10−4 |
Bipolar disorder | ||||||
Paranoia and hallucinations | −0.032 | −0.048 | −0.018 | −0.045 | 0.022 | .039 |
Anhedonia | −0.022 | −0.041 | −0.002 | 0.008 | 0.028 | .767 |
Cognitive disorganization | 0.008 | −0.013 | 0.029 | 0.021 | 0.028 | .451 |
Parent‐rated negative symptoms | −0.010 | −0.026 | 0.006 | 0.009 | 0.021 | .669 |
Major depressive disorder | ||||||
Paranoia and hallucinations | 0.004 | −0.018 | 0.026 | 0.013 | 0.020 | .523 |
Anhedonia | 0.065 | 0.037 | 0.094 | 0.061 | 0.023 | 7.50 × 10−3 |
Cognitive disorganization | 0.033 | 0.005 | 0.062 | 0.015 | 0.028 | .594 |
Parent‐rated negative symptoms | 0.023 | 0.010 | 0.042 | 0.031 | 0.020 | .119 |
Statistically significant results are highlighted in bold.
Genetic covariance.