Table 2.
Inflammatory bowel disease phenotype using montreal classification in Cuban immigrants diagnosed in the United States, stratified by period of immigration
| Total N | Period of immigration | |||
|---|---|---|---|---|
| <1980 | 1980‐1994 | 1995‐present | P‐valuea | |
| 44 | 42 | 44 | ||
| Mean time from immigration to IBD diagnosis | 31.7 (12.8) | 17.13 (8.5) | 8.30 (4.7) | <.001 b |
| Mean age of IBD diagnosis (SD) | 44.5 (16.4) | 33.7 (14.0) | 33.7 (11.9) | <.001 b |
| Crohn's disease (%) | 29 (65.9) | 24 (57.1) | 31 (70.5) | .396 |
| Ulcerative colitis (%) | 15 (34.1) | 18 (42.9) | 13 (29.5) | |
| Crohn's disease (n) | 29 | 24 | 31 | |
| Upper GI Crohn's | 0 (0) | 1 (2.4) | 2 (4.5) | .399 |
| Ileal | 13 (29.5) | 8 (19.0) | 12 (27.3) | .996 |
| Colonic | 4 (9.0) | 3 (7.1) | 7 (15.9) | |
| Ileocolonic | 12 (27.3) | 11 (53.4) | 12 (27.3) | |
| Ulcerative colitis (n) | 15 | 18 | 13 | |
| Proctitis | 1 (6.7) | 1 (5.6) | 1 (7.7) | .275 |
| Left sided colitis | 7 (46.7) | 9 (50.0) | 1 (7.7) | |
| Pancolitis | 7 (46.7) | 8 (44.4) | 9 (69.2) | |
| Crohn's behaviour | ||||
| Fibrostenotic | 15 (34.1) | 13 (30.9) | 9 (31.0) | .187 |
| Inflammatory | 17 (38.6) | 9 (21.4) | 17 (38.6) | |
| Internal perforating | 6 (13.6) | 3 (7.1) | 5 (11.4) | |
| Perianal perforating | 4 (13.8) | 9 (42.9) | 12 (37.5) | .055c |
| IBD‐related surgeries | 20 (45.5) | 15 (35.7) | 14 (31.8) | .397 |
| Abdominal surgeries for Crohn's disease | 13 (44.8) | 11 (45.8) | 10 (32.3) | .501 |
| Total proctocolectomy ulcerative colitis | 1 (6.6) | 1 (5.5) | 0 (0) | .675 |
| Perianal surgeries | 1 (3.4) | 3 (12.5) | 5 (16.1) | .251 |
| Hospitalisations | 21 (47.7) | 26 (61.9) | 13 (29.5) | .112 |
Phenotypic information was missing on a few patients. Certain patients with Crohn's disease had upper gastroenterology tract disease and ileal or colonic disease and therefore the sum of n for disease location of Crohn's and for Crohn's disease behaviour is greater than the total number of Crohn's patients.
P‐value is comparing differences across the three time‐cohorts.
P‐value after taking into account covariates (gender and age of immigration) in univariate analysis of variance.
P‐value for perianal disease was attenuated to nonsignificance (.055) after taking into account duration of disease using logistic regression.
Bold values correspond to p‐values <.05.