Figure 2.

Evolutionarily conserved amino acid positions and mean evolutionary conservation rates for each TLR21 motif. A, The conservation scale ranges from 1 to 9; each glade has a different color, and glades 1 and 9 represent the most variable and most conserved residue positions, respectively. The sequence of Gallus TLR21 (gTLR21) is used to indicate the 9‐color conservation grade system. The signal peptide, each predicted LRR modules of the ectodomain (ECD), transmembrane region (TM), and intracellular domain (TIR) for gTLR21 are labeled. B, The different modules of the gTLR21 protein are represented by their identifying numbers. The lowest score represents the most conserved position in the protein