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. 2018 May 12;14(7):775–783. doi: 10.7150/ijbs.26077

Figure 5.

Figure 5

Model for Atg7 inhibiting Warburg effect by suppressing PKM2 phosphorylation resulting reduced EMT. Atg7 interacts with PKM2 directly and inhibits PKM2 phosphorylation. PKM2 dephosphorylation inhibits the Warburg effect, thereby inhibiting EMT. See text for details.