Figure 6.

Mean (± standard deviation) absolute changes in Numeric Rating Scale (NRS). Subjects were treated with placebo, 1% or 3% JTE‐052 ointment twice daily for 7 days in the morning and the evening with a 12‐h interval. The assessment of NRS was performed twice daily from day −1 (hospitalization) to day 9 (1 day after the end of application); (a) the period “from bedtime to morning awakening” was assessed at morning awakening and (b) the period “from morning awakening to bedtime” was assessed at bedtime.