Table 3.

Associations Between Changes in BMI and Telomere Attrition

	ΔLTL*
	Percent Difference	95% CI
Annual BMI change, kg/m2	−1.01	−3.14 to 1.13
Adjusted for baseline BMI	−0.93	−3.09 to 1.24
Annual weight change, kg	−0.25	−1.02 to 0.52
Adjusted for baseline weight	−0.26	−1.04 to 0.51
Annual waist circumference change, cm	−0.60	−1.31 to 0.10
Adjusted for baseline waist circumference	−0.59	−1.32 to 0.14
Annual hip circumference change, cm	−0.65	−1.57 to 0.26
Adjusted for baseline hip circumference	−0.69	−1.63 to 0.26

Note: All models were Adjusted for sex, childhood SEP, and adulthood SEP. Baseline measurements refer to measurements at age 53 years. BMI = body mass index; LTL = leukocyte telomere length.

*Annual percentage change in LTL.