Table 2.
Comparison between observed and expected hits stratified by phenotype.
| Nominal p-value | Expected hits per phenotype A | Number of hits per phenotype |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BMI | Ed_Att | Neuro-ticism | Alzheimer | Schizo-phrenia | Well-being | Aggressive behavior | Anxiety | Depressive Symptoms | MDD | Bipolar disorder | Autism | Internalizing problems | ADHD | ||
| p ≤ 0.001 | 0.216 | 11 | 8 | 2 | 2 | 14 | 1 | 1 | 4 | 2 | |||||
| p ≤ 0.0001 | 0.0216 | 9 | 4 | 2 | 9 | 1 | 1 | ||||||||
| p ≤ 0.00001 | 0.00216 | 5 | 1 | 1 | 3 | 1 | |||||||||
| p ≤ 0.000001 | 0.000216 | 2 | 1 | 1 | |||||||||||
| p ≤ 0.0000001 | 0.0000216 | 2 | 1 | ||||||||||||
| p ≤ 0.00000001 | 0.00000216 | 1 | 1 | ||||||||||||
Expected number of false positive hits was computed as follows: 0.001 x 216=0.216 for p-value≤0.001.
ADHD Attention Deficit/Hyperactivity Disorder; BMI, Body Mass Index; Ed_Att: Educational attainment.
A
Based on the identified 216 chromosomal regions of 1 MB (see Methods online).