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Whole-body phenotype and glucose metabolism of aging female IL-18R−/− mice. A: Body weight for 32, 36, 55, and 72 weeks old animals (CON-: n = 28 IL-18R−/− n = 42). B: Gonadal, retroperitoneal, and inguinal fat pads in 72 weeks old fasted animals (CON-: n = 10; IL-18R−/− n = 13); C: Oral glucose tolerance with area under the curve (AUC) inserted in 72 weeks old animals (CON: n = 8; IL-18R−/− n = 10). Results are presented as mean ± SEM. *p < 0.05 (A, B, C) and **p < 0.01 vs CON (B).
