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. 2018 Apr 12;12:89–97. doi: 10.1016/j.molmet.2018.04.005

Figure 5.

Figure 5

Ovariectomized IL-18R−/− mice exhibit impaired insulin signaling in liver. Total and phosphorylated Ser473 Akt during Sham and OVX in liver (A), muscle (B), and adipose tissue (C) before and after insulin stimulation. No Insulin (−); Insulin stimulation (+). Samples from Sham and OVX were run on the same gel and related to total Akt. (n = 4–6 per group). Results are presented as mean ± SEM. *p < 0.05 vs CON Sham, KO Sham, CON OVX (two-way ANOVA: Class: 4 groups (CONsham CON-OVX KOsham KO-OVX) and Insulin × 4 groups). (*) = p = 0.056 vs CONsham.