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. 2018 May 9;68(671):e394–e400. doi: 10.3399/bjgp18X696221

Table 4.

Fixed-effects meta-analysis of apparent treatment-resistant hypertension according to additional criteria

Analysis Prevalence estimate (95% CI) I2
Applying a threshold of 140/90 mmHg to all patients 0.09 (0.09 to 0.10) 0.76

And
Applying a threshold of 130/80 mmHg for patients with diabetes or chronic kidney disease 0.10 (0.09 to 0.11) 0.74

And
Applying a threshold of 150/80 mmHg for patients >80 years regardless of morbidity 0.09 (0.08 to 0.10) 0.76

And
Applying a threshold of adequate dosing in all medications (WHO-DDD) 0.04 (0.04 to 0.05) 0.83

And
Applying a threshold of adequate adherence (>75% prescriptions) 0.03 (0.03 to 0.04) 0.80

CI = confidence interval. WHO-DDD = World Health Organization-defined daily dosing. I2 is the percentage of variance in the meta-analysis that is attributable to study heterogeneity.