Table 3. Person Correlations between MRS markers and MRI markers of vascularity, CBV, CBF, and ktrans) as well as between MRS markers and PET markers of tumor hypoxia (SUVmax).
| Metabolic ratio | ROI | nrCBV (R) | nCBF (R) | Median ktrans (R) |
SUV max (R) |
|---|---|---|---|---|---|
| NAA/Cho | Tumor | -0.38 | -0.41 | -0.08 | -0.33 |
| Cho/Cr | Tumor | 0.24 | 0.28 | -0.02 | 0.03 |
| Lac/Cr | Tumor | -0.27 | -0.25 | -0.06 | -0.29 |
| Lac/NAA | Tumor | -0.02 | -0.01 | 0.23 | -0.18 |
| NAA/Cho | Periphery | -0.33 | -0.34 | 0.14 | -0.41 |
| Cho/Cr | Periphery | 0.17 | 0.20 | -0.27 | 0.11 |
| Lac/Cr | Periphery | -0.09 | -0.11 | 0.10 | -0.15 |
| Lac/NAA | Periphery | -0.01 | -0.01 | 0.33 | -0.04 |
(nRCBV: relative cerebral blood volume, corrected for leakage effects and normalized to normal-appearing white matter; nCBF: cerebral blood flow, normalized to normal-appearing white matter; ktrans: vascular permeability; SUV standardized uptake value