Figure 6.

Fgl2 ^−/− mice have increased central memory, effector memory after lymphocytic choriomeningitis virus clone 13 (LCMV cl‐13) infection. Total CD8⁺ (CD8⁺ CD44^high CD62L^low) and CD4⁺ (CD4⁺ CD44^high CD62L^low) effector memory cells in the spleen in both fgl2 ^+/+ and fgl2 ^−/− mice pre‐infection and at day 56 post infection (p.i.) (a, c) were analysed. Virus‐specific CD8⁺ (CD8⁺ Tet_Gp33‐41 ⁺ CD44^high CD62L^low) (b) and CD4⁺ (CD4⁺ Tet_Gp61‐80 ⁺ CD44^high CD62L^low) (d) effector memory cells were also determined at day 56 p.i. Total CD8⁺ (CD8⁺ CD44^high CD62L^high) and CD4⁺ (CD4⁺ CD44^high CD62L^high) central memory cells were determined from both fgl2 ^+/+ and fgl2^−/− mice both pre‐infection and at day 56 p.i. (e, f). Data are presented as the means ± SEM of five mice per group and time‐point from three independent experiments *P < 0·05.