Figure 7.

Fgl2 ^−/− mice have enhanced production of neutralizing antibody after lymphocytic choriomeningitis virus clone 13 (LCMV cl‐13) infection. Total LCMV‐specific IgG was measured using an LCMV IgG specific ELISA (a). Data are presented as the mean absorbance at 450 nm × dilution of plasma ± SEM of five mice per group and per time‐point from one independent experiment *P < 0·05. (b) Total neutralizing antibody titres were measured in the plasma from LCMV‐infected mice. The graph shows the dilution of plasma required for 50% plaque reduction of 200 PFU of LCMV cl‐13 in a standard LCMV focus‐forming assay. Data represent the log₂ mean ± SEM of five mice per group and per time‐point from one independent experiment *P < 0·05.