Table 3.
Descriptive statistics of facial scarring grades, lesion counts, pre- and post-treatment in subjects who had complete data through the study period and a post-treatment follow-up (16 subjects)
| Facial scaring grades and lesion counts | Pre-treatment and treatment phase | Post-treatment phase | ANOVA (F, p value) | ||
|---|---|---|---|---|---|
| Baseline | Week 16 | Week 24 | Week 48–72 | ||
| Scarring | |||||
| Scarring grade | 3.43 (0.51) a,b,c | 3.06 (0.92) a,d | 2.62 (0.88)b,d | 2.93 (0.85)b,c | 2.74; p = 0.051 |
| Subject scar assessment | – | 3.06 (0.57) | 3.06 (0.44) | 2.93 (0.68) | 0.25; p = 0.77 |
| Investigator scar assessment | – | 2.81 (1.10) b,c | 3.75 (1.39) a,c | 1.62 (0.80) a,b | 14.28; p < 0.0001 |
| Lesion counts | |||||
| Icepick scars | 9.12 (5.00) | 7.68 (4.04) | 7.56 (4.81) | 5.68 (4.79) | 1.45; p = 0.23 |
| Boxcar scars | 7.06 (6.06) | 4.31 (2.93) | 3.93 (2.46) | 5.50 (4.47) | 1.77; p = 0.16 |
| Rolling scars | 1.56 (1.89) | 0.87 (1.02) | 0.56 (1.15) | 0.75 (1.12) | 1.68; p = 0.18 |
* Treatment average was taken from baseline through week 24. Post hoc tests (Tukey) were performed; subscript letters show where significant differences (p < 0.05) occur between time points (i.e., means for subscript ‘a’ are significantly different from one another, etc.)