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. 2018 Mar 21;11(3):619–627. doi: 10.1016/j.tranon.2018.02.013

Figure 2.

Figure 2

Integrin αvβ6 increases IL-8 expression in lung cancer cells. A549 and H460 cells were transfected with integrin αvβ6 siRNA or nonspecific control siRNA. (A) The mRNA levels of integrin αvβ6 and IL-8 in lung cancer cells A549 and H460 were detected by qRT-PCR analysis. GAPDH was used as a control. (B) Western blots were performed to detect protein levels of MAPK along with their phosphorylation. GAPDH was used as a control. (C) Luciferase activity was detected in A549 cells. Bars indicate the mean ± SEM, *P < .05 vs. control group.