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. 2018 Jun 14;8:9153. doi: 10.1038/s41598-018-27492-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Global gene expression. In the chart, the inner ring corresponds to the total number of genes statistically significant, among these the gray part (4368) represents the common genes differentially expressed in both conditions, which are control (CTR-hPDLSCs) and cells treated with 0.5 μM of moringin (MORINGIN-hPDLSCs). Instead the two remaining small parts of the inner ring indicate the number of genes expressed only in the CTR-hPDLSCs (10) and in the MORINGIN-hPDLSCs (12). In the second ring the portion of common genes is divided into upregulated (2076) and downregulated (2292) genes. The third ring shows the genes upregulated (40) and downregulated (234) that have a Log2 Fold Change (LFC) > 2.