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. 2018 Jun 14;8:9153. doi: 10.1038/s41598-018-27492-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Differentially expressed genes involved in cerebral cortex development induced by 0.5 μM of moringin. Heat maps show differentially expressed genes that have Log2FoldChange (LFC) > 2 (red scale) and a q-value (FDR) < 0.05, hence genes that after treatment with 0.5 μM of moringin appear overexpressed and statistically significant. The expression’s values in the two conditions, CTR-hPDLSCs and MORINGIN-hPDLSCs, are indicated through the FPKM (Fragments Per Kilobase of exon model per Million mapped fragments) and graphically depicted in green scale, where a different intensity of color represents a differential gene expression, that is also reported in column 4 as fold change value (red color). In column 4 a more intense red color is associated to a higher fold change value. Gene cluster and stage association analyzed by Cortecon database were also shown.