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. 2018 Jun 14;8:9158. doi: 10.1038/s41598-018-26746-1

Table 2.

NXT reduces urinary microalbumin excretion in db/db mice.

Time of treatment (days) Urea nitrogen (mM) Urine creatinine (μM) Urine microalbumin (μg/24 h) UAlb/UCr (μg/μM)
Control NXT Control NXT Control NXT Control NXT
45 122.6 ± 11.5 128.6 ± 10.7 106.6 ± 18.6 116.5 ± 12.4 229.6 ± 23.1 61.19 ± 4.47 2.05 ± 0.21 0.47 ± 0.03
70 115.7 ± 10.0 117.2 ± 8.3 95.6 ± 13.6 97.0 ± 10.0 274.6 ± 20.4 31.3 ± 13.1 2.21 ± 0.16 0.36 ± 0.05
96 118.3 ± 9.6 119.5 ± 7.2 93.1 ± 6.6 97.3 ± 3.7 281.2 ± 16.1 29.8 ± 6.91 2.16 ± 0.12 0.38 ± 0.04

During the treatment as indicated in Fig. 1, db/db mice were placed in metabolic chambers at the indicated time points of treatment to collect urine samples for a 24 h duration. Levels of nitrogen, creatinine and microalbumin excreted in urine were determined, respectively. UCr: urine creatinine; UAlb: urine microalbumin. p < 0.05 vs. db/db control mice (n = 10).