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. 2018 Jun 14;8:9100. doi: 10.1038/s41598-018-27518-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Results of the four combinations of simulated transmission modes and hygiene-level scenarios with sensitivity reduced to 20% of the original. (A) ITM model with normal hygiene. (B) ITM model with low hygiene. (C) DTM model with normal hygiene. (D) DTM model with low hygiene. Black indicates no control and red indicates test-and-cull. Solid lines represent the median, dashed lines show the smoothed 50% simulation envelope and dotted lines show the smoothed 90% simulation envelope.