Table 1.

Affinities of the investigated indoles, indazoles and carbazoles at the cannabinoid CB₁ and CB₂ receptors determined in radioligand binding assays

^aFluorometric imaging plate reader membrane potential assay system from Molecular Devices (Sunnyvale, CA, USA)

^bRadioligand binding study versus 0.5 nM [³H]CP55,940

^cRadioligand binding study versus 0.62 nM [³H]CP55,940

^dHomogenous time resolved fluorescence-based cAMP accumulation