Table 2.
Distribution and association of individual predictors with treatment failure
| Treatment success N = 519 (92%) |
Treatment failure N = 46 (8%) |
|||
|---|---|---|---|---|
| Diagnostic variable1 | Frequency (%)3 | Frequency (%) | p value | OR (95% CI) |
| Patient history | ||||
| Female gender, N (%) | 305 (59) | 33 (72) | 0.092 | 1.78 (0.92–3.46) |
| Age in years, mean (SD) | 58 (13) | 63 (12) | 0.024 | 1.03 (1.01–1.06) |
| ASA score > 2, N (%) | 45 (9) | 8 (17) | 0.052 | 2.22 (0.98–5.04) |
| Duration of complaints in days, median (IQR) | 3 (1–5) | 3 (1–10) | 0.345 | 1.03 (1.002–1.05) |
| Nausea, N (%) | 203 (39) | 18 (39) | 0.822 | 1.04 (0.55–1.97) |
| Vomiting, N (%) | 40 (8) | 7 (15) | 0.132 | 2.01 (0.79–5.11) |
| Generalized abdominal pain, N (%) | 30 (6) | 4 (9) | 0.432 | 1.55 (0.52–4.62) |
| Change in bowel habit | 0.653 | |||
| Diarrhea, N (%) | 69 (13) | 8 (17) | 1.43 (0.62–3.28) | |
| Obstipation, N (%) | 79 (15) | 6 (13) | 0.85 (0.32–2.24) | |
| Alternating, N (%) | 37 (7) | 4 (10) | 1.41 (0.47–4.17) | |
| Rectal blood loss, N (%) | 33 (6) | 5 (11) | 0.182 | 1.93 (0.72–5.17) |
| Physical examination | ||||
| No rebound tenderness, N (%) | 336 (65) | 36 (78) | 0.062 | 2.02 (0.94–4.33) |
| Active muscle resistance, N (%) | 81 (16) | 9 (20) | 0.532 | 1.28 (0.58–2.82) |
| Temperature in Celsius, mean (SD) | 37.3 (0.7) | 37.3 (0.6) | 0.764 | 0.93 (0.60–1.46) |
| Blood tests | ||||
| CRP (mg/L), mean (SD) | 92 (66) | 121 (85) | 0.014 | 1.01 (1.001–1.01) |
| Leucocytes(109/L), mean (SD) | 11.8 (3.4) | 12.3 (3.6) | 0.374 | 1.04 (0.96–1.13) |
| CRP findings | ||||
| Pericolic free air, N (%) | 35 (7) | 6 (13) | 0.122 | 2.06 (0.82–5.19) |
| Treatment | ||||
| Hospital admittance, N (%)6 | 267 (51) | 34 (74) | < 0.012 | 2.67 (1.35–5.28) |
All results in this table are results of multiple imputation and based on univariable logistic regression
Abbreviations: ASA American Society of Anesthesiologists, SD standard deviation, IQR inter quartile range, OR odds ratio, CI confidence interval, CRP C-reactive protein
1Variables are coded such that the reported category indicate a higher risk of treatment failure
2Chi-square test
3Fisher exact test
4Independent T test
5Mann-Whitney U test
6Within 24 h after presentation