Table 3.
Test statistics for general linear models (two-way ANOVA with repeated measurements design) assessing differences in biomarkers between baseline and follow-up examinations (main effects score), differences in biomarker levels between stress cohort and control group (main effect group), and, whether temporal developments of biomarker levels vary between groups (interaction group × biomarker).
| Main effect biomarker | Main effect group | Interaction group × biomarker | |
|---|---|---|---|
| AUCg | F = 3.243 df1 = 1, df2 = 62 partial η² = 0.050 p = 0.077, pBH = n.s. |
F = 14.846 df1 = 1, df2 = 62 partial η² = 0.193 p < 0.001, pBH < 0.001 |
F = 0.025 df1 = 1, df2 = 62 partial η² < 0.001 p = 0.875, pBH = n.s. |
| AUCi | F = 0.032 df1 = 1, df2 = 62 partial η² = 0.001 p = 0.858, pBH = n.s. |
F = 0.014 df1 = 1, df2 = 62 partial η² < 0.001 p = 0.905, pBH = n.s. |
F = 1.210 df1 = 1, df2 = 62 partial η² = 0.019 p = 0.276, pBH = n.s. |
| Cortisol midday | F = 10.608 df1 = 1, df2 = 62 partial η² = 0.146 p = 0.002, pBH < 0.01 |
F = 16.158 df1 = 1, df2 = 62 partial η² = 0.207 p < 0.001, pBH < 0.001 |
F = 5.999 df1 = 1, df2 = 62 partial η² = 0.088 p = 0.017, pBH < 0.01 |
| Cortisol nadir | F = 0.636 df1 = 1, df2 = 63 partial η² = 0.010 p = 0.428, pBH = n.s. |
F = 19.847 df1 = 1, df2 = 63 partial η² = 0.0240 p < 0.001, pBH < 0.001 |
F = 4.434 df1 = 1, df2 = 63 partial η² = 0.066 p = 0.039, pBH = n.s. |
| MPO | F = 0.787 df1 = 1, df2 = 62 partial η² = 0.013 p = 0.378, pBH = n.s. |
F = 2.012 df1 = 1, df2 = 62 partial η² = 0.031 p = 0.161, pBH = n.s. |
F = 0.082 df1 = 1, df2 = 62 partial η² = 0.001 p = 0.775, pBH = n.s. |
| HCYS | F = 0.263 df1 = 1, df2 = 61 partial η² = 0.004 p = 0.610, pBH = n.s. |
F = 0.632 df1 = 1, df2 = 61 partial η² = 0.010 p = 0.430, pBH = n.s. |
F = 0.758 df1 = 1, df2 = 61 partial η² = 0.012 p = 0.387, pBH = n.s. |
| IL6 | F = 0.650 df1 = 1, df2 = 63 partial η² = 0.010 p = 0.423, pBH = n.s. |
F = 4.122 df1 = 1, df2 = 63 partial η² = 0.061 p = 0.047, pBH = n.s. |
F = 0.879 df1 = 1, df2 = 63 partial η² = 0.014 p = 0.352, pBH = n.s. |
Effect sizes are given as partial η². P-values given as pBH have been adjusted according to Benjamini and Hochberg. Df, degrees of freedom; AUCg, area under the curve with respect to ground; AUCi, cortisol awakening response – area under the curve with respect to increase; MPO, plasma myeloperoxidase; HCYS, homocysteine; IL6, interleukin 6.