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. 2018 Jun;50(2):77–82.

Table 1.

Cases of VWD workup during STMCS.

Case Age/Gender STMCS Device Indication for VWD Workup Blood Products Used During STMCS HMWMs (%) IMWMs (%) LMWMs (%) VWF Ag VWF Activity F8 Device Outcome
1 59/M Impella 5.0 Hemoptysis None 3 46 51 Removed; OHT
2 40/F Impella 5.0 Epistaxis 10 PRBCs 4 59 37 Removed; OHT
3 69/M ECMO Hemoptysis 16 PRBCs, 1 FFP, 5 platelets 4 61 34 229 157 346 Removed; LVAD
4 73/M Impella 5.0 Hemoptysis None 3 60 37 222 210 318 Removed; OHT
5 56/M ECMO ↓ Hgb None 6 60 34 Expired
6 72/M ECMO ↓ Hgb 2 PRBCs 3 59 38 400 252 366 Removed; RVAD
7 60M ECMO GI bleed 5 PRBCs, 4 FFPs, 3 Platelets, 1 cryo 5 62 33 118 96 108 Removed
8 37/M Impella 5.0 Epistaxis None 4 49 47 291 237 434 Removed; OHT
9 57/M Impella 5.0, RVAD GI bleed 7 PRBCs, 2 platelets 2 52 46 Expired
10 40/M Impella 5.0 ↓ Hgb 3 PRBCs 2 52 46 Expired
11 74/M Impella 5.0, RVAD ↓ Hgb 10 PRBCs, 1 platelets 5 60 35 Expired
12 57/F Impella 5.0 GI bleed 10 PRBCs 2 59 38 Removed
13 57/F Impella CP ↓ Hgb 2 PRBCs, 3 FFPs 3 64 33 400 261 372 Expired
14 40/F Impella 5.0 ↓ Hgb None 5 59 37 Removed; LVAD
15 66/M ECMO ↓ Hgb 12 PRBCs 2 60 38 201 141 210 Removed
16 30/M Impella 5.0 GI bleed 7 PRBCs, 5 FFPs, 1 platelets 5 61 34 268 67 210 Removed
17 67/M Impella 5.0 ↓ Hgb 11 PRBCs, 6 FFPs, 1 platelet 4 62 34 400 330 714 Expired
18 50/M Impella 5.0 ↓ Hgb 2 PRBCs, 1 FFP 2 56 43 400 460 410 Removed

Ag, antigen; Cryo, cryoprecipitate; ECMO, extracorporeal membrane oxygenation; F, female; FFPs, fresh frozen plasma; GI, gastrointestinal; Hgb, hemoglobin; HMWMs, high molecular weight multimers; IMWM, intermediate molecular weight multimers; LMWMs, low molecular weight multimers; LVAD, left ventricular assist device; M, male; OHT, orthotopic heart transplantation; PRBCs, packed red blood cells; RVAD, right ventricular assist device; STMCS, short-term mechanical support; VWD, von Willebrand disease; VWF, von Willebrand factor.