Figure 5.

Effect of β-arr2 on CCL22–induced activation of mitogen-activated protein kinases (MAPKs) in Th2 cells. The time course of CCL22-induced Th2 cell production of (A and B) P-p38 and (C and D) P-ERK1/2 was assessed by immunoblot and quantified by densitometry. Open bars, WT Th2 cells; solid bars, β-arr2–KO Th2 cells. Western blot is representative of three separate experiments. Data are expressed as mean (±SEM). *P < 0.05 significant difference between WT and β-arr2–KO Th2 cells at the indicated time point according to Student’s t test. Readers may view the uncut gels for C in the data supplement.