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. 2018 May 21;58(6):240–246. doi: 10.2176/nmc.ra.2018-0026

Table 1.

Incidence of late cerebrovascular events* after surgery in the literature of pediatric moyamoya disease, stratified by population size and length of follow-up

Size F/u length Authors Treatment No. of cases Mean F/u period (years) F/u rate (%) No. of late ischemic strokes (%) No. of late hemorrhagic strokes (%) Overall incidence of stroke (% per year)
Large Extremely-long Mukawa et al.6) Indirect 172 14.3 83 3 (1.7) 3 (1.7) 0.24
Funaki et al.8)§ Direct (combined) 58 18.1 96.6 1 (1.7) 3 (5.2) 0.41
Imaizumi et al.4) Various 25 18.8 80.6 1 (4.0) 3 (12.0) 0.85

Large Long Bao et al.9) Indirect 288 4.4 N/A 8 (2.8) 2 (0.7) 9.00
Scott et al.16) Indirect 126 5.1 99.2 4 (3.2) 0 NA
Kuroda et al.10) Direct (combined) 28 6.1 N/A 0 0 0
Rashad et al.14) Direct (combined) 23 6.4 95.7 0 0 0

Small Extremely-long Isono et al.18) Indirect 11 12.8 N/A 0 0 0
Goda et al.17) Indirect 6 15.2 N/A 0 0 0

Small Long Darvish et al.15) Various 16 7.3 N/A 1 (6.3) 0 N/A
*

Excludes perioperative strokes,

“Large” indicates number of patients exceeds 20,

“Extremely long” indicates a mean F/u period exceeding 10 years,

§

The authors’ group,

Includes perioperative strokes.