FIG 2.

Viral replication and histopathology assessments of Vc_BR60 and Ym_WI01 in the lungs of mice. (A and B) Viral replication of Vc_BR60 (WT and mouse-adapted strains) (A) and Ym_WI01 (WT and mouse-adapted strains) (B) in the mouse lungs was determined at 1, 3, and 5 dpi. The results were averaged from the viral titers determined from three different mice. PBS was used for mock infection. Error bars denote SD. *, P < 0.5; **, P < 0.01 (compared with the titers of Vc_BR60 and Ym_WI01, respectively). (C) For lung histopathology assessment, H&E-stained slides were examined under a light microscope (magnification, ×100).