TABLE 1.
Results of confirmatory assays for H. sapiens ISGs
| Rank | Gene symbol | Product name | Fold inhibition (ISGs/empty SCRPSY) |
|---|---|---|---|
| 1 | IRF1 | Interferon regulatory factor 1 | 13.94188652 |
| 2 | IFITM3 | Interferon-induced transmembrane protein 3 | 10.81898208 |
| 3 | ISG20 | Interferon-stimulated exonuclease gene, 20 kDa | 10.51226219 |
| 4 | EHD4 | EH domain-containing protein 4 | 8.337769295 |
| 5 | NOS2A | Nitric oxide synthase 2a | 8.142114105 |
| 6 | INDO/IDO | Indoleamine-pyrrole 2,3-dioxygenase | 7.431693179 |
| 7 | SCO2 | SCO cytochrome oxidase-deficient homolog 2 | 6.682186081 |
| 8 | HK2 | Hexokinase 2 | 6.600853655 |
| 9 | BCL3 | B-cell CLL/lymphoma 3 | 5.560601225 |
| 10 | IRF7 | Interferon regulatory factor 7 | 4.996490044 |
| 11 | C5ORF39 | Annexin A2 receptor | 4.532151199 |
| 12 | NUP50 | Nucleoporin, 50 kDa | 4.502720506 |
| 13 | OAS2 | 2′,5′-Oligoadenylate synthetase 2 | 3.857183543 |
| 14 | TLK2 | Tousled-like kinase 2 | 3.560273013 |
| 15 | PXK | PX domain-containing serine/threonine kinase-like protein | 3.333094361 |
| 16 | MX1 | Myxovirus (influenza virus) resistance 1 | 3.019964468 |
| 17 | IFIT5 | Interferon-induced protein with tetratricopeptide repeats 5 | 2.697749553 |
| 18 | LGALS9 | Galectin 9, beta-galactoside-binding protein | 2.222739332 |
| 19 | CCNA1 | Cyclin A1 | 2.017553608 |
| 20 | TNFRSF10A | Tumor necrosis factor receptor superfamily, member 10a | 1.181220011 |