TABLE 2.
Results of confirmatory assays for M. mulatta ISGs
| Rank | Gene symbol | Product name | Fold inhibition (ISGs/empty SCRPSY) |
|---|---|---|---|
| 1 | IFNβ1 | Beta interferon 1 | 25.68764253 |
| 2 | ISG20 | Interferon-stimulated exonuclease gene, 20 kDa | 16.51376275 |
| 3 | INDO/IDO | Indoleamine-pyrrole 2,3-dioxygenase | 11.89015349 |
| 4 | LGALS9 | Galectin 9, beta-galactoside-binding protein | 6.99430233 |
| 5 | PFKFB3 | 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 5.758834317 |
| 6 | RHOB | Ras homolog family member B | 5.195047578 |
| 7 | BCL3 | B-cell CLL/lymphoma 3 | 4.754072894 |
| 8 | TLK2 | Tousled-like kinase 2 | 4.709891813 |
| 9 | ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3, isotype | 4.611043388 |
| 10 | IRF7 | Interferon regulatory factor 7 | 4.174521863 |
| 11 | CCNA1 | Cyclin A1 | 3.389544757 |
| 12 | IFITM3 | Interferon-induced transmembrane protein 3 | 3.301078884 |
| 13 | HK2 | Hexokinase 2 | 3.060345699 |
| 14 | PXK | PX domain-containing serine/threonine kinase-like protein | 2.855499432 |
| 15 | IRF1iso3 | Interferon regulatory factor 1, isotype | 2.770775682 |
| 16 | IFITM3 | Interferon-induced transmembrane protein 3 | 2.64956607 |
| 17 | IFITM2 | Interferon-induced transmembrane protein 2 | 2.495300874 |
| 18 | IFIT5 | Interferon-induced protein with tetratricopeptide repeats 5 | 1.868064022 |
| 19 | ZNF385B | Zinc finger protein 385B | 1.802174105 |
| 20 | TNFRSF10A | Tumor necrosis factor receptor superfamily, member 10a | 1.363085906 |