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SUN1 overexpression specifically inhibits infections by HIV-1 and HIV-2 but not those by SIV or MLV. HEK293A cells transduced with an empty lentivector (EV) or a lentivector expressing SUN1-Flag were infected with the indicated VSV_G-pseudotyped, luciferase-expressing viral vectors. At 48 h postinfection, luciferase activity was measured. Data presented are means ± SD for three independent experiments.
