FIG 2.

IFN-I signaling in hematopoietic cells is essential for surviving SFTSV infection. (A) Effect of bone marrow cell transplantation on the survival curve of SFTSV-infected mice. (B) Virus titers in peripheral blood of infected bone marrow-chimeric mice at 2 dpi. (C and D) Cytokine levels in serum (C) and relative expression of cytokine mRNA in the spleen (D) in SFTSV-infected chimeric mice at the indicated time points. Representative data from two independent experiments are shown (B to D) and plotted as means ± standard deviations (SD) (B). *, P < 0.05; **, P < 0.01; #, not significant.