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. 2018 Jun 13;92(13):e00082-18. doi: 10.1128/JVI.00082-18

TABLE 3.

Similarities between predicted polyprotein cleavage sites of MHAV and HAVa

Virus Predicted cleavage site
P1
P2
P3
VP4/VP2 VP2/VP3 VP3/VP1-PX VP1-px/2B 2B/2C 2C/3A 3A/3B 3B/3C 3C/3D
HAV LSLA/DIEE LSTQ/MMRN VTTQ/VGDD LFSQ/AKIS LRTQ/SFSN LWSQ/GISD IPAE/GVYH VESQ/STLE IESQ/RIMK
MHAV LSLA/DVEE IMTQ/MMRN TVAQ/AGDD VCSQ/SGPI LHTQ/GFSD LWSQ/SGDD IPAC/GVYH AESQ/STLE IESQ/RIMK
a

The HAV reference sequence under accession no. NC_001489 was used. Amino acids in bold indicate conserved residues.