FIG 5.

The innervation of mouse corneal epithelium is heterogeneous. (A) Overview of mouse corneal epithelial innervation based on previously published data (39–41). (B) A representative z-stack projection of corneal epithelium from adult CGRP-GFP mice. Tissue sections were immunostained for β3-Tub (blue), and CGRP⁺ neurons were green from GFP expression in the transgenic mouse. The merged image is shown at the bottom (DAPI [4′,6-diamidino-2-phenylindole] is in white). Blue arrowheads point to CGRP⁻ FNEs. Green arrowheads point to CGRP⁺ FNEs. L, long; S, short.