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Characterization of the 5- and 4-track G4 motif in the promoter sequence of the human NEIL3 gene by (A) 1H-NMR, (B) CD, and (C) Tm with and without OG. Positions of the loop and core OGs in the primary sequence are marked with the red lightning symbols and are red. Only the CD spectra for the 4-track sequences, which share similar profiles with the 5-track sequences, are shown here for brevity. Error bars correspond to 95% confidence intervals derived from triplicate trials.
