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. Author manuscript; available in PMC: 2019 May 22.

Published in final edited form as: Biochemistry. 2018 May 10;57(20):2958–2970. doi: 10.1021/acs.biochem.8b00226

(A) The T_m dependence on K⁺ concentration. : 5-NEIL3 native, : 5-NEIL3 loop OG, : 5-NEIL3 core OG, : 4-NEIL3 native, : 4-NEIL3 loop OG, : 4-NEIL3 core OG. (B) Tabulated list of van’t Hoff-derived K⁺ ion coordination values and favorable ΔG for the formation of each NEIL3 G4 sequences.

Inline graphic — (A) The T_m dependence on K⁺ concentration. : 5-NEIL3 native, : 5-NEIL3 loop OG, : 5-NEIL3 core OG, : 4-NEIL3 native, : 4-NEIL3 loop OG, : 4-NEIL3 core OG. (B) Tabulated list of van’t Hoff-derived K⁺ ion coordination values and favorable ΔG for the formation of each NEIL3 G4 sequences.