Table 1.

Oligonucleotide sequences used in the thioflavin T fluorescence enhancement assay.^*

Name of oligonucleotide	Description	Primary Sequence
hTel G4	human telomeric G-quadruplex sequence	5′-TAGGGTTAGGGTTAGGGTTAGGGTT-3′
c-myc G4	c-myc G-quadruplex sequence (2,3,4,5 G-track)	5′-TGAGGGTGGGGAGGGTGGGGAA-3′
4-NEIL3 native	unmodified 4 G-track NEIL3 G-quadruplex sequence	5′-TTGGGCGGGGCCTGGGCGGGGCC-3′
5-NEIL3 native	unmodified 5 G-track NEIL3 G-quadruplex sequence	5′-TAGGGTGCTGTTTGGGCGGGGCCTGGGCGGGGCC-3′
4-NEIL3 loop OG	4-NEIL3 with OG in the loop position	5′-TTGGGC $\underset{¯}{\mathrm{G}}$GGGCCTGGGCGGGGCC-3′
5-NEIL3 loop OG	5-NEIL3 with OG in the loop position	5′-TAGGGTGCTGTTTGGGC $\underset{¯}{\mathrm{G}}$GGGCCTGGGCGGGGCC-3′
4-NEIL3 core OG	4-NEIL3 with OG in the core position	5′-TTGGGCGGGGCCT $\underset{¯}{\mathrm{G}}$GGCGGGGCC-3′
5-NEIL3 core OG	5-NEIL3 with OG in the core position	5′-TAGGGTGCTGTTTGGGCGGGGCCT $\underset{¯}{\mathrm{G}}$GGCGGGGCC-3′
hTel triplex	human telomeric triplex (one G-run is replaced with a T-run)	5′-TAGGGTTAGGGTTATTTTTAGGGTT-3′
4-NEIL3 C-rich	ssDNA C-rich complementary strand of 4-NEIL3 native	5′-GGCCCCGCCCAGGCCCCGCCCAA-3′
5-NElL3 C-rich	ssDNA C-rich complementary strand of 5-NEIL3 native	5′-GGCCCCGCCCAGGCCCCGCCCAAACAGCACCCTA-3′
DNA duplex	DNA duplex combined from the G- and C-rich complementary strands of 4-NEIL3 native	(a) 5′-TTGGGCGGGGCCTGGGCGGGGCC-3′ (b)3′-AACCCGCCCCGGACCCGCCCCGG-5′

^*The synthetically incorporated OGs are indicated by the red Gs.