Table 2.

Cost parameters (in 2015 US dollars) for events within model.

Costs
	Base Case	Min	Max	Source
Surgery without AE	$12,952	$12,522	$13,381	HCUP*
Surgery with Grade 3 or 4 AE	$39,651	$37,701	$41,601	HCUP*
Admission for Grade 3 or 4 Chemotherapy-related AE	$9,089	$8,776	$9,402	HCUP*
Total Surgical Procedure Cost
PCS	$2,829	$2,622	$3,036	CMS †
NACT	$1,709	$1,583	$1,834	CMS †
Base Surgery Cost
PCS	$2,199	$2,040	$2,358	CMS†
NACT	$1,501	$1,392	$1,611	CMS †
Chemotherapy Administration‡
Infusion Costs Per Cycle	$221			CMS †
Chemotherapy Cost Per Cycle	$112			CMS †
Total Chemotherapy Cost Per 3 Cycles	$999	$899	$1,099	CMS †

^*Data for inpatient stays in 2013;

^†Medicare reimbursement database maintained by the American Medical Association;

^‡Chemotherapy administration costs do not include supportive care medications (e.g. steroids, diphenhydramine, antiemetics).

Abbreviations: AE: adverse event; PCS: primary cytoreductive surgery; NACT: neoadjuvant chemotherapy; HCUP: Agency for Healthcare Quality and Research’s Healthcare Cost and Utilization Project; CMS: Centers for Medicare and Medicaid Services.