Table 3.

Estimated rates of additional procedures during cytoreductive surgery – either primary or interval cytoreduction.

Rates of Additional Procedure
Procedure	PCS Base Case	Min	Max	ICS Base Case	Min	Max	Cost*	Source
Small bowel resection †, ‡, §, ‖	0.141	0.067	0.215	0.041	0.006	0.077	$1358	CMS¶
Large bowel resection †, ‡, §, ‖	0.218	0.104	0.331	0.071	0.005	0.138	$1491	CMS¶
Upper abdominal surgery (splenectomy) †, §, ‖	0.391	0	0.978	0.158	0.051	0.265	$288	CMS¶

^*In 2015 US dollars. Rates estimated from aggregate data from

^†EORTC 55971,

^‡CHORUS,

^§SCORPION, and

^‖Meyer, et al.[6,7,9,13] in a random-effects meta-analytic model.

^¶Medicare reimbursement database maintained by the American Medical Association.

Abbreviations: PCS: primary cytoreductive surgery; ICS: interval cytoreductive surgery; CMS: Centers for Medicare and Medicaid Services.