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. 2018 Jun 8;8:164. doi: 10.3389/fcimb.2018.00164

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Copyright © 2018 Truong, Suriyanarayanan, Zeng, Le, Liu, Li, Tong, Wang and Seneviratne.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene ontology analysis of genes with higher expression in resistant strains when exposed to SM21. SM21-resistant haploid strains at mid-log phrase (10⁸ cell/ml) were treated with 2 μg/ml of SM21 for 1 or 4 h. RNA was extracted and sent for RNA sequencing. Differential expression analysis was first applied to determined genes which were upregulated in the resistant haploid strains under SM21 exposure. Subsequent gene ontology analysis illustrated biological processes which were significantly higher in the resistant haploid strains under SM21 treatment.