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. 2018 Jun 8;8:164. doi: 10.3389/fcimb.2018.00164

Table 1.

Changes in gene expression related to complexes in electron transport chain and assembly factors in GZY803 under SM21 exposure.

Gene Function Log2 fold change
1 h 4 h
NADH DEHYDROGENASE
NDH51 Potential mitochondrial Complex I −1.2 −1.1
FESUR1 Potential mitochondrial Complex I −0.8 −0.6
NDE1 Potential NADH dehydrogenase −0.7 −0.4
YMX6 Potential NADH dehydrogenase 0.4 0.006
COMPLEX II
SDH1 Succinate dehydrogenase, flavoprotein subunit 0.2 0.3
SDH2 Succinate dehydrogenase, iron-sulfur subunit −0.4 −0.6
SDH4 Succinate dehydrogenase 0.4 0.4
COMPLEX III
QCR2 Cytochrome b-c1 complex subunit 2 −1.4 −1.5
QCR7 Cytochrome b-c1 complex subunit 7 −1.2 −1.4
RIP1 Cytochrome b-c1 complex subunit Rieske −1.2 −1.5
COMPLEX IV
COX4 Cytochrome c oxidase subunit 4 −1.2 −1.8
COX7 Cytochrome c oxidase subunit 7 −0.8 −1.2
COX13 Cytochrome c oxidase subunit 6A −1.5 −1.6
COMPLEX V
ATP1 ATP synthase subunit alpha −1.3 −1.7
ATP2 ATP synthase subunit beta −1.1 −1.5
ATP3 ATP synthase subunit gamma −1.3 −1.6
ATP4 F1F0 ATP synthase subunit 4 −1 −1.5
ATP5 F1F0 ATP synthase subunit 5 −1.2 −1.4
ATP7 ATP synthase subunit d −1.3 −1.7
ATP16 F1F0 ATP synthase subunit delta −0.4 −0.6
ATP20 F1F0 ATP synthase subunit g −1.3 −1.6
ASSEMBLY FACTORS
orf19.4324 Possible mitochondrial Complex I 0.6 0.3
orf19.4727 Succinate dehydrogenase assembly factor 2 0.4 0.1
SHD7 Succinate dehydrogenase assembly factor 3 0 −0.1
CBP4 Assembly factor CBP4 0.9 1.1
COX11 Uncharacterized protein Cox11p 0.8 0.6
COX15 Uncharacterized protein Cox15p 1.4 1.4
COX16 Cytochrome c oxidase assembly protein COX16 0.5 0.6
COX19 Cytochrome c oxidase assembly protein COX19 0.9 1
COX20 Cytochrome c oxidase protein 20 0.2 0.2
COX23 Cytochrome c oxidase-assembly factor COX23 0.9 0.7
ATP12 ATP synthase complex assembly protein −0.00006 −0.008